The development of modern life sciences would not be complete without mice. As the most widely used mammalian animal model, mouse research contributes to the understanding of biological phenomena through the use of multiple tools such as gene editing, optogenetics, and various imaging techniques. Our laboratory aims to identify the smallest molecular and neuroscientific unit responsible for the sleep-wake cycle in mice and elucidate its conserved minimal unit by comparing it with other species. Keywords: synaptic plasticity, gene editing, electrophysiology, optogenetics, epigenetics

Modern life science, which has developed around mouse research, has reached a turning point. As of 2023, useful tools that were previously limited to mice research can now be applied to other organisms. As Dr. August Krogh stated in Krogh's Law: "For such a large number of problems, there will be some animal of choice, or a few such animals, on which it can be most conveniently studied.", it is now possible to choose the right species for the questions we have fostered. In our laboratory, we focus on ants, which are social insects, and study how genetically homogeneous ants can acquire phenotypic diversity. Keywords: sociality, gene editing, electrophysiology, mass spectrometry, epigenetics

Data science and mathematical modeling play an important role in the complex system of life, which consists of trillions of cells with billions of base pairs and their interactions. In our laboratory, we aim to unravel the underlying laws of complex biological phenomena by analyzing multimodal data and constructing mathematical models. Keywords: machine learning, differential equations, time series analysis, bioinformatics